Dynamic spatio-temporal contribution of single β5t+ cortical epithelial precursors to the thymus medulla
Intrathymic T-cell development is critically dependent on cortical and medullary thymic epithelial cells (TECs). Both epithelial subsets originate during early thymus organogenesis from progenitor cells that express the thymoproteasome subunit β5t, a typical feature of cortical TECs. Using in vivo l...
Main Authors: | , , , , , , , , , , , , |
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格式: | Journal article |
語言: | English |
出版: |
Wiley
2016
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