Dynamic spatio-temporal contribution of single β5t+ cortical epithelial precursors to the thymus medulla
Intrathymic T-cell development is critically dependent on cortical and medullary thymic epithelial cells (TECs). Both epithelial subsets originate during early thymus organogenesis from progenitor cells that express the thymoproteasome subunit β5t, a typical feature of cortical TECs. Using in vivo l...
Glavni autori: | Mayer, C, Žuklys, S, Zhanybekova, S, Ohigashi, I, Teh, H, Sansom, S, Shikama-Dorn, N, Hafen, K, Macaulay, I, Deadman, M, Ponting, C, Takahama, Y, Holländer, G |
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Format: | Journal article |
Jezik: | English |
Izdano: |
Wiley
2016
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