Side-chain ionization states in a potassium channel.
KcsA is a bacterial K+ channel that is gated by pH. Continuum dielectric calculations on the crystal structure of the channel protein embedded in a low dielectric slab suggest that side chains E71 and D80 of each subunit, which lie adjacent to the selectivity filter region of the channel, form a pro...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
2001
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