Side-chain ionization states in a potassium channel.

KcsA is a bacterial K+ channel that is gated by pH. Continuum dielectric calculations on the crystal structure of the channel protein embedded in a low dielectric slab suggest that side chains E71 and D80 of each subunit, which lie adjacent to the selectivity filter region of the channel, form a pro...

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Bibliographic Details
Main Authors: Ranatunga, K, Shrivastava, I, Smith, G, Sansom, MS
Format: Journal article
Language:English
Published: 2001