Association between active genes occurs at nuclear speckles and is modulated by chromatin environment.

Genes on different chromosomes can be spatially associated in the nucleus in several transcriptional and regulatory situations; however, the functional significance of such associations remains unclear. Using human erythropoiesis as a model, we show that five cotranscribed genes, which are found on...

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Bibliographic Details
Main Authors: Brown, J, Green, J, das Neves, R, Wallace, H, Smith, A, Hughes, J, Gray, N, Taylor, S, Wood, W, Higgs, D, Iborra, F, Buckle, V
Format: Journal article
Language:English
Published: 2008