Tacrolimus pharmacology and nonclinical studies: from FK506 to protopic.
Tacrolimus (FK506) is a calcineurin inhibitor with potent immunomodulating properties. It has been marketed worldwide since 1993-1994 for the rejection of liver and kidney transplants (Prograf). The pharmacologic properties of tacrolimus resulted in its development as an ointment for the treatment o...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2001
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