Mutation of von Hippel-Lindau tumour suppressor and human cardiopulmonary physiology

Background: The von Hippel–Lindau tumour suppressor protein–hypoxia-inducible factor (VHL–HIF)pathway has attracted widespread medical interest as a transcriptional system controlling cellular responses to hypoxia, yet insights into its role in systemic human physiology remain limited. Chuvash polyc...

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Bibliographic Details
Main Authors: Smith, T, Brooks, J, Balanos, G, Lappin, T, Layton, D, Leedham, D, Liu, C, Maxwell, P, McMullin, M, McNamara, C, Percy, M, Pugh, C, Ratcliffe, P, Talbot, N, Treacy, M, Robbins, P
Other Authors: Barnes, P
Format: Journal article
Language:English
Published: Public Library of Science 2006
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