Targeting base excision repair to improve cancer therapies.
Most commonly used cancer therapies, particularly ionizing radiation and certain classes of cytotoxic chemotherapies, cause cell death by damaging DNA. Base excision repair (BER) is the major system responsible for the removal of corrupt DNA bases and repair of DNA single strand breaks generated spo...
Главные авторы: | , |
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Формат: | Journal article |
Язык: | English |
Опубликовано: |
2007
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