Targeting base excision repair to improve cancer therapies.

Most commonly used cancer therapies, particularly ionizing radiation and certain classes of cytotoxic chemotherapies, cause cell death by damaging DNA. Base excision repair (BER) is the major system responsible for the removal of corrupt DNA bases and repair of DNA single strand breaks generated spo...

Полное описание

Библиографические подробности
Главные авторы: Sharma, R, Dianov, G
Формат: Journal article
Язык:English
Опубликовано: 2007