Synthesis of an eight carbon homologue of alpha-homomannojirimycin via a bicyclic aminolactone

A thermally induced intramolecular 1,3-dipolar cycloaddition of an azidoester and subsequent sodium cyanoborohydride reduction of the resulting bicyclic vinylogous urethane to give a bicyclic aminolactone allows access to an eight carbon homologue of α-homomannojirimycin which is a weak fucosidase i...

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Bibliografiske detaljer
Main Authors: Shilvock, J, Hsia, K, Nash, R, Lloyd, J, Winters, A, Asano, N, Fleet, G
Format: Journal article
Sprog:English
Udgivet: 1998