Identification and selection of novel mycobacterial antigens using immunopeptidomics and immunoinformatics for the development of subunit vaccines against tuberculosis
<p>In response to the urgent need for an effective vaccine against tuberculosis (TB), mass spectrometry-based immunopeptidomics was employed to identify novel mycobacterial antigens. Human macrophages (differentiated THP-1 cells) were utilised as an in-vitro model of TB, in which mycobacterial...
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| Format: | Thesis |
| Language: | English |
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2022
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