Thioredoxin inhibitors attenuate platelet function and thrombus formation

Thioredoxin (Trx) is an oxidoreductase with important physiological function. Imbalances in the NADPH/thioredoxin reductase/thioredoxin system are associated with a number of pathologies, particularly cancer, and a number of clinical trials for thioredoxin and thioredoxin reductase inhibitors have b...

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Bibliographic Details
Main Authors: Metcalfe, C, Ramasubramoni, A, Pula, G, Harper, M, Mundell, S, Coxon, C
Format: Journal article
Published: Public Library of Science 2016