The analysis of DNA interstrand cross-links and their repair by the modified comet assay
DNA interstrand cross-links (ICLs) are an extremely toxic form of DNA damage that cells experience upon exposure to natural metabolites. Moreover, ICLs are cytotoxic lesions produced by a range of clinically important anticancer agents. Therefore, improving our understanding of ICL induction and pro...
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Book section |
| Language: | English |
| Published: |
Humana Press
2020
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