Clinical efficacy of launched JAK inhibitors in rheumatoid arthritis

Tofacitinib and baricitinib are the first orally available, small-molecule inhibitors of JAK enzymes to be approved for the treatment of RA. Tofacitinib is a selective JAK1,3 inhibitor with less activity against JAK2 and TYK2 and baricitinib a selective, oral JAK1,2 inhibitor with moderate activity...

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Bibliographic Details
Main Author: Taylor, P
Format: Journal article
Published: Oxford University Press 2019