Direct imaging of DNA in living cells reveals the dynamics of chromosome formation

Individual chromosomes are not directly visible within the interphase nuclei of most somatic cells; they can only be seen during mitosis. We have developed a method that allows DNA strands to be observed directly in living cells, and we use it to analyze how mitotic chromosomes form. A fluorescent a...

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Bibliographic Details
Main Authors: Manders, E, Kimura, H, Cook, P
Format: Journal article
Language:English
Published: Rockefeller University Press 1999
Subjects: