T₂-weighted MRI detects presymptomatic pathology in the SOD1 mouse model of ALS.

Neuroinflammation has been identified as a potential therapeutic target in amyotrophic lateral sclerosis (ALS), but relevant biomarkers are needed. The superoxide dismutase (SOD1)(G93A) transgenic mouse model of ALS offers a unique opportunity to study and potentially manipulate presymptomatic patho...

Descripción completa

Detalles Bibliográficos
Autores principales: Evans, M, Serres, S, Khrapitchev, A, Stolp, H, Anthony, D, Talbot, K, Turner, M, Sibson, N
Formato: Journal article
Lenguaje:English
Publicado: 2014