A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory

A protective vaccine against hepatitis C virus (HCV) remains an unmet clinical need. HCV infects millions of people worldwide and is a leading cause of liver cirrhosis and hepatocellular cancer. Animal challenge experiments, immunogenetics studies, and assessment of host immunity during acute infect...

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Bibliographic Details
Main Authors:	Swadling, L, Capone, S, Antrobus, R, Brown, A, Richardson, R, Newell, E, Halliday, J, Kelly, C, Bowen, D, Fergusson, J, Kurioka, A, Ammendola, V, Del Sorbo, M, Grazioli, F, Esposito, M, Siani, L, Traboni, C, Hill, A, Colloca, S, Davis, M, Nicosia, A, Cortese, R, Folgori, A, Klenerman, P, Barnes, E
Format:	Journal article
Language:	English
Published:	American Association for the Advancement of Science 2014

A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory

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