Loss of major histocompatibility complex-encoded transporter associated with antigen presentation (TAP) in colorectal cancer.
Presentation of endogenous antigenic peptides to cytotoxic T lymphocytes (CTLs) is mediated by the major histocompatibility complex (MHC) class I molecules. These antigenic peptides derived from the cytoplasmic protein pool are transported by the recently described MHC-encoded transporters (TAP1 and...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1994
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