Loss of major histocompatibility complex-encoded transporter associated with antigen presentation (TAP) in colorectal cancer.

Loss of major histocompatibility complex-encoded transporter associated with antigen presentation (TAP) in colorectal cancer.

Presentation of endogenous antigenic peptides to cytotoxic T lymphocytes (CTLs) is mediated by the major histocompatibility complex (MHC) class I molecules. These antigenic peptides derived from the cytoplasmic protein pool are transported by the recently described MHC-encoded transporters (TAP1 and...

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Bibliographic Details
Main Authors:	Kaklamanis, L, Townsend, A, Doussis-Anagnostopoulou, I, Mortensen, N, Harris, A, Gatter, K
Format:	Journal article
Language:	English
Published:	1994

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