A simple and cost-effective method for producing small interfering RNAs with high efficacy.

Small interfering RNAs (siRNAs) are powerful RNA interference (RNAi) reagents for directed post- transcriptional gene silencing. Exogenous siRNA is frequently used in RNAi studies. However, due to profound differences in the activity of siRNAs targeted to different regions of a gene, several reagent...

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Bibliographic Details
Main Authors: Sohail, M, Doran, G, Riedemann, J, Macaulay, V, Southern, E
Format: Journal article
Language:English
Published: 2003