Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID

General transcription factor TFIID is a key component of RNA polymerase II transcription initiation. Human TFIID is a megadalton-sized complex comprising TATA-binding protein (TBP) and 13 TBP-associated factors (TAFs). TBP binds to core promoter DNA, recognizing the TATA-box. We identified a ternary...

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Bibliographic Details
Main Authors: Gupta, K, Watson, A, Baptista, T, Scheer, E, Chambers, A, Koehler, C, Zou, J, Obong-Ebong, I, Kandiah, E, Temblador, A, Round, A, Forest, E, Man, P, Bieniossek, C, Laue, E, Lemke, E, Rappsilber, J, Robinson, C, Devys, D, Tora, L, Berger, I
Format: Journal article
Language:English
Published: eLife Sciences Publications 2017