Delivery of the malaria virulence protein PfEMP1 to the erythrocyte surface requires cholesterol-rich domains.

The particular virulence of the human malaria parasite Plasmodium falciparum derives from export of parasite-encoded proteins to the surface of the mature erythrocytes in which it resides. The mechanisms and machinery for the export of proteins to the erythrocyte membrane are largely unknown. In oth...

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Bibliographic Details
Main Authors: Frankland, S, Adisa, A, Horrocks, P, Taraschi, T, Schneider, T, Elliott, SR, Rogerson, S, Knuepfer, E, Cowman, A, Newbold, C, Tilley, L
Format: Journal article
Language:English
Published: 2006