Probing molecular interactions in intact antibody: antigen complexes, an electrospray time-of-flight mass spectrometry approach.

Using a combination of nanoflow-electrospray ionization and time-of-flight mass spectrometry we have analyzed the oligomeric state of the recombinant V antigen from Yersinia pestis, the causative agent of plague. The mass spectrometry results show that at pH 6.8 the V antigen in solution exists pred...

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Bibliographic Details
Main Authors: Tito, M, Miller, J, Walker, N, Griffin, K, Williamson, E, Despeyroux-Hill, D, Titball, R, Robinson, C
Format: Journal article
Language:English
Published: 2001