Control of heterologous hepatitis C virus infection in chimpanzees is associated with the quality of vaccine-induced peripheral T-helper immune response.

Prophylactic hepatitis C virus (HCV) vaccine trials with human volunteers are pending. There is an important need for immunological end points which correlate with vaccine efficacy and which do not involve invasive procedures, such as liver biopsies. By using a multicomponent DNA priming-protein boo...

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Bibliographic Details
Main Authors: Rollier, C, Depla, E, Drexhage, J, Verschoor, E, Verstrepen, B, Fatmi, A, Brinster, C, Fournillier, A, Whelan, J, Whelan, M, Jacobs, D, Maertens, G, Inchauspé, G, Heeney, J
Format: Journal article
Language:English
Published: 2004