Two monoclonal anti-human T lymphocyte antibodies have similar biologic effects and recognize the same cell surface antigen.

Two independently produced monoclonal antibodies, UCHT1, an IgG1 antibody, and OKT3, an IgG2 antibody, which specifically identify all human peripheral T lymphocytes, were shown to possess similar functional properties. Both were highly mitogenic to peripheral blood T lymphocytes, and UCHT1 blocked...

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Bibliographic Details
Main Authors: Burns, G, Boyd, A, Beverley, P
Format: Journal article
Language:English
Published: 1982