Oxetane cis- and trans-beta-amino-acid scaffolds from L-rhamnose by efficient S(N)2 reactions in oxetane rings; pseudoenantiomeric analogues of the antibiotic oxetin
An efficient multigram ring contraction of a 1,4-lactone 2-O-triflate derived from l-rhamnose - with retention of configuration in the ring closure - is the key step in the preparation of a series of oxetanes, which are pseudoenantiomeric analogues of the naturally occurring antibiotic oxetin, an ox...
| Glavni autori: | , , , , , |
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| Format: | Journal article |
| Jezik: | English |
| Izdano: |
2004
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