The T309G MDM2 gene polymorphism is a novel risk factor for proliferative vitreoretinopathy.

Proliferative vitreoretinopathy (PVR) is still the major cause of failure in retinal detachment (RD) surgery. It is believed that down-regulation in the p53 pathway could be an important key in PVR pathogenesis. The purpose was to evaluate the impact of T309G MDM2 polymorphism (rs2279744) in PVR. Di...

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Bibliographic Details
Main Authors: Pastor-Idoate, S, Rodríguez-Hernández, I, Rojas, J, Fernández, I, García-Gutiérrez, M, Ruiz-Moreno, J, Rocha-Sousa, A, Ramkissoon, Y, Harsum, S, Maclaren, R, Charteris, D, Vanmeurs, J, González-Sarmiento, R, Pastor, J
Format: Journal article
Language:English
Published: Public Library of Science 2013