Cell-cycle modulation of transcription termination factor Sen1

Many non-coding transcripts (ncRNA) generated by RNA polymerase II in S. cerevisiae are terminated by the Nrd1-Nab3-Sen1 complex. However, Sen1 helicase levels are surprisingly low compared with Nrd1 and Nab3, raising questions regarding how ncRNA can be terminated in an efficient and timely manner....

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Bibliographic Details
Main Authors: Mischo, H, Chun, Y, Harlen, K, Smalec, B, Dhir, S, Churchman, L, Buratowski, S
Format: Journal article
Published: Cell Press 2018