Association of the BTNL2 rs2076530 single nucleotide polymorphism with Graves' disease appears to be secondary to DRB1 exon 2 position beta74.

OBJECTIVE: The HLA region encodes numerous immune response genes, with the DR/DQ molecules consistently associated with autoimmune disease (AID). Recent studies in sarcoidosis have identified association of a single nucleotide polymorphism (SNP) rs2076530 within BTNL2, a potential T-cell inhibitor,...

詳細記述

書誌詳細
主要な著者: Simmonds, M, Heward, J, Barrett, J, Franklyn, J, Gough, S
フォーマット: Journal article
言語:English
出版事項: 2006