A model invalidation-based approach for elucidating biological signalling pathways, applied to the chemotaxis pathway inR. sphaeroides

Background Developing methods for understanding the connectivity of signalling pathways is a major challenge in biological research. For this purpose, mathematical models are routinely developed based on experimental observations, which also allow the prediction of the system behaviour under differ...

ver descrição completa

Detalhes bibliográficos
Principais autores: Roberts, M, August, E, Hamadeh, A, Maini, P, McSharry, P, Armitage, J, Papachristodoulou, A
Formato: Journal article
Publicado em: Biomedical Central 2009