APOE alleles predict the rate of cognitive decline in Alzheimer disease: a nonlinear model.

APOE alleles predict the rate of cognitive decline in Alzheimer disease: a nonlinear model.

BACKGROUND: The APOE genotype predicts the age at onset of Alzheimer disease (AD) and neuropathologic progression. However, studies relating APOE alleles to the rate of cognitive decline have been inconclusive. This may stem from their use of linear statistical analyses. OBJECTIVE: To model relation...

ver descrição completa

Detalhes bibliográficos
Main Authors:	Martins, C, Oulhaj, A, de Jager, C, Williams, J
Formato:	Journal article
Idioma:	English
Publicado em:	2005

Registos relacionados

Homocysteine as a predictor of cognitive decline in Alzheimer's disease.
Por: Oulhaj, A, et al.
Publicado em: (2010)

Homocysteine as a predictor of cognitive decline in Alzheimer's disease
Por: Oulhaj, A, et al.
Publicado em: (2010)

An increased rate of longitudinal cognitive decline is observed in Parkinson's disease patients with low CSF Aß42 and an APOE ε4 allele
Por: Marian Shahid, et al.
Publicado em: (2019-07-01)

Disentangling sex-dependent effects of APOE on diverse trajectories of cognitive decline in Alzheimer's disease
Por: Haixu Ma, et al.
Publicado em: (2024-04-01)

Cognitive declines precede and predict functional declines in aging and Alzheimer's disease.
Por: Laura B Zahodne, et al.
Publicado em: (2013-01-01)

Protective effect of the APOE-e3 allele in Alzheimer’s disease
Por: B.V.P. de-Almada, et al.
Publicado em: (2012-01-01)

Effect of apolipoprotein E ε4 allele on the progression of cognitive decline in the early stage of Alzheimer's disease
Por: Kazushi Suzuki, et al.
Publicado em: (2020-01-01)

Protective effect of the APOE-e3 allele in Alzheimer’s disease
Por: B.V.P. de-Almada, et al.
Publicado em: (2012-01-01)

Omega-3 Fatty Acid Status Enhances the Prevention of Cognitive Decline by B Vitamins in Mild Cognitive Impairment
Por: Oulhaj, A, et al.
Publicado em: (2016)

Rate of progression of cognitive decline in Alzheimer's disease: effect of butyrylcholinesterase K gene variation.
Por: Holmes, C, et al.
Publicado em: (2005)

Amyloid-β and APOE genotype predict memory decline in cognitively unimpaired older individuals independently of Alzheimer’s disease polygenic risk score
Por: Jori Tomassen, et al.
Publicado em: (2022-12-01)

Predictive Factors of Rapid Cognitive Decline in Patients with Alzheimer Disease
Por: Coralie Barbe, et al.
Publicado em: (2016-12-01)

Periodontitis and Cognitive Decline in Alzheimer's Disease.
Por: Mark Ide, et al.
Publicado em: (2016-01-01)

Neuroticism alters the transcriptome of the frontal cortex to contribute to the cognitive decline and onset of Alzheimer’s disease
Por: Céline H. De Jager, et al.
Publicado em: (2021-02-01)

Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease
Por: Allen, G, et al.
Publicado em: (2016)

APOE GENE POLYMORPHISM: THE IMPACT OF APOE4 ALLELE ON SYSTEMIC INFLAMMATION AND ITS ROLE IN THE PATHOGENESIS OF ALZHEIMER’S DISEASE
Por: I. K. Malashenkova, et al.
Publicado em: (2018-06-01)

Plasma biomarkers for diagnosis of Alzheimer's disease and prediction of cognitive decline in individuals with mild cognitive impairment
Por: Pia Kivisäkk, et al.
Publicado em: (2023-03-01)

Predicting progression and cognitive decline in amyloid-positive patients with Alzheimer’s disease
Por: Hákon Valur Dansson, et al.
Publicado em: (2021-09-01)

Postmortem serotoninergic correlates of cognitive decline in Alzheimer's disease.
Por: Lai, M, et al.
Publicado em: (2002)

Plasma biomarkers of Alzheimer’s disease improve prediction of cognitive decline in cognitively unimpaired elderly populations
Por: Nicholas C. Cullen, et al.
Publicado em: (2021-06-01)

APOE epsilon 4 allele affects presynaptic, but not postsynaptic cholinergic markers in Alzheimer's disease neocortex
Por: Lai, M, et al.
Publicado em: (2006)

Selective effects of the APOE epsilon4 allele on presynaptic cholinergic markers in the neocortex of Alzheimer's disease.
Por: Lai, M, et al.
Publicado em: (2006)

A TOMM40/APOE allele encoding APOE‐E3 predicts high likelihood of late‐onset Alzheimer’s disease in autopsy cases
Por: Selma M. Soyal, et al.
Publicado em: (2020-08-01)

MRI Markers of Small Vessel Disease and the APOE Allele in Cognitive Impairment
Por: Mana Shams, et al.
Publicado em: (2022-07-01)

The role of APOE in cognitive trajectories and motor decline in Parkinson’s disease
Por: Sungyang Jo, et al.
Publicado em: (2021-04-01)

Resistance and resilience to tau pathology in Alzheimer's disease: Effects of age, sex, and APOE alleles
Por: Yury Loika, et al.
Publicado em: (2024-10-01)

Rates of decline in Alzheimer disease decrease with age.
Por: Dominic Holland, et al.
Publicado em: (2012-01-01)

Predicting cognitive decline in healthy older adults.
Por: De Jager, C, et al.
Publicado em: (2005)

PSEN1 polymorphisms alter the rate of cognitive decline in sporadic Alzheimer's disease patients.
Por: Belbin, O, et al.
Publicado em: (2009)

Dietary fats and the APOE-e4 risk allele in relation to cognitive decline: a longitudinal investigation in a biracial population sample
Por: Xiaoran Liu, et al.
Publicado em: (2024-05-01)

Effect of APOE and CD33 on Cognitive Decline.
Por: Kathleen M Hayden, et al.
Publicado em: (2015-01-01)

Alzheimer’s and neurodegenerative disease biomarkers in blood predict brain atrophy and cognitive decline
Por: Heather E. Dark, et al.
Publicado em: (2024-04-01)

Modelling prognostic trajectories of cognitive decline due to Alzheimer's disease
Por: Joseph Giorgio, et al.
Publicado em: (2020-01-01)

Selective effects of the APOE ε4 allele on presynaptic cholinergic markers in the neocortex of Alzheimer's disease
Por: Mitchell K.P. Lai, et al.
Publicado em: (2006-06-01)

Impact of atrial fibrillation on the cognitive decline in Alzheimer’s disease
Por: Taizen Nakase, et al.
Publicado em: (2023-01-01)

Metabolic syndrome biomarkers relate to rate of cognitive decline in MCI and dementia stages of Alzheimer’s disease
Por: Jagan A. Pillai, et al.
Publicado em: (2023-03-01)

Multimodal Discrimination between Normal Aging, Mild Cognitive Impairment and Alzheimer’s Disease and Prediction of Cognitive Decline
Por: Corinna M. Bauer, et al.
Publicado em: (2018-02-01)

Structural Network Efficiency Predicts Resilience to Cognitive Decline in Elderly at Risk for Alzheimer’s Disease
Por: Florian U. Fischer, et al.
Publicado em: (2021-02-01)

Inflammatory pathway analytes predicting rapid cognitive decline in MCI stage of Alzheimer’s disease
Por: Jagan A. Pillai, et al.
Publicado em: (2020-07-01)

Correction: Effect of APOE and CD33 on Cognitive Decline.
Por: Kathleen M Hayden, et al.
Publicado em: (2015-01-01)