Cofactor Strap regulates oxidative phosphorylation and mitochondrial p53 activity through ATP synthase.

Metabolic reprogramming is a hallmark of cancer cells. Strap (stress-responsive activator of p300) is a novel TPR motif OB-fold protein that contributes to p53 transcriptional activation. We show here that, in addition to its established transcriptional role, Strap is localised at mitochondria where...

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Xehetasun bibliografikoak
Egile Nagusiak: Maniam, S, Coutts, A, Stratford, MR, McGouran, J, Kessler, B, La Thangue, N
Formatua: Journal article
Hizkuntza:English
Argitaratua: Nature Publishing Group 2015