Cytoskeletal tension actively sustains the migratory T‐cell synaptic contact

When migratory T cells encounter antigen‐presenting cells (APCs), they arrest and form radially symmetric, stable intercellular junctions termed immunological synapses which facilitate exchange of crucial biochemical information and are critical for T‐cell immunity. While the cellular processes unde...

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Bibliographic Details
Main Authors: Kumari, S, Mak, M, Poh, Y-C, Tohme, M, Watson, N, Melo, M, Janssen, E, Dustin, M, Geha, R, Irvine, DJ
Format: Journal article
Language:English
Published: EMBO Press 2020