The loss of the PDE6 deactivating enzyme, RGS9, results in precocious light adaptation at low light levels.

The GTPase activating protein, RGS9-1, is vital for the deactivation and regulation of the phototransduction cascade (C. K. Chen et al., 2000; C. W. Cowan, R. N. Fariss, I. Sokal, K. Palczewski, and T. G. Wensel, 1998; W. He, C. W. Cowan, and T. G. Wensel, 1998; A. L. Lyubarsky et al., 2001). Its lo...

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Bibliographic Details
Main Authors: Stockman, A, Smithson, H, Webster, A, Holder, G, Rana, N, Ripamonti, C, Sharpe, LT
Format: Journal article
Language:English
Published: 2008