Becalming type 17 inflammation in ulcerative colitis
Genome-wide association studies in ulcerative colitis point to a role for FcγRIIA, a receptor for IgG. Castro-Dopico et al. (2019) find a profound induction of anti-commensal IgG in the colonic mucosa of UC patients and outline a pathway whereby FcγR activation by IgG triggers IL-1β production, type...
| Auteurs principaux: | , |
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| Format: | Journal article |
| Langue: | English |
| Publié: |
Elsevier
2019
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