Pathways for Holliday junction processing during homologous recombination in Saccharomyces cerevisiae.

The Saccharomyces cerevisiae Rmi1 protein is a component of the highly conserved Sgs1-Top3-Rmi1 complex. Deletion of SGS1, TOP3, or RMI1 is synthetically lethal when combined with the loss of the Mus81-Mms4 or Slx1-Slx4 endonucleases, which have been implicated in Holliday junction (HJ) resolution....

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Bibliographic Details
Main Authors: Ashton, T, Mankouri, H, Heidenblut, A, McHugh, P, Hickson, I
Format: Journal article
Language:English
Published: 2011