Addition of functional human telomeres to YACs.

Linear mammalian artificial chromosomes (MACs) will require functional telomeres, a centromere and the ability to replicate autonomously. We are investigating the possibility of developing MACs from yeast artificial chromosomes (YACs). Retrofitting vectors have been constructed to replace YAC telome...

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Main Authors: Taylor, S, Larin, Z, Smith, C
格式: Journal article
语言:English
出版: 1994