Addition of functional human telomeres to YACs.

Linear mammalian artificial chromosomes (MACs) will require functional telomeres, a centromere and the ability to replicate autonomously. We are investigating the possibility of developing MACs from yeast artificial chromosomes (YACs). Retrofitting vectors have been constructed to replace YAC telome...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Taylor, S, Larin, Z, Smith, C
التنسيق: Journal article
اللغة:English
منشور في: 1994