Mapping of HLA genes using pulsed-field gradient electrophoresis.

The technique of pulsed-field gradient electrophoresis (PFGE) allows the determination of gene linkage relationships since DNA fragments up to 2 Mb can be separated. PFGE was employed to study linkage of class I, II and III genes belonging to the human major histocompatibility (HLA) complex. The res...

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Bibliographic Details
Main Authors: Ragoussis, J, van der Bliek, A, Trowsdale, J, Ziegler, A
Format: Journal article
Language:English
Published: 1986