Mapping of HLA genes using pulsed-field gradient electrophoresis.

The technique of pulsed-field gradient electrophoresis (PFGE) allows the determination of gene linkage relationships since DNA fragments up to 2 Mb can be separated. PFGE was employed to study linkage of class I, II and III genes belonging to the human major histocompatibility (HLA) complex. The res...

Descripción completa

Detalles Bibliográficos
Autores principales: Ragoussis, J, van der Bliek, A, Trowsdale, J, Ziegler, A
Formato: Journal article
Lenguaje:English
Publicado: 1986