Effect of ileal bile acid transporter inhibitor GSK2330672 on pruritus in primary biliary cholangitis: a double-blind, randomised, placebo-controlled, crossover, phase 2a study

<p><strong>Background</strong> Up to 70% of patients with primary biliary cholangitis develop pruritus (itch) during the course of their disease. Treatment of pruritus in primary biliary cholangitis is challenging and novel therapies are needed. Ursodeoxycholic acid, the standard f...

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Bibliographic Details
Main Authors: Hegade, VS, Kendrick, SFW, Dobbins, RL, Miller, SR, Thompson, D, Richards, D, Storey, J, Dukes, GE, Corrigan, M, Elferink, RPJ, Beuers, U, Hirschfield, GM, Jones, DE
Format: Journal article
Language:English
Published: Elsevier 2017