Quantification of PtdInsP3 molecular species in cells and tissues by mass spectrometry
Class I phosphoinositide-3-kinase (PI3K) isoforms generate the intracellular signaling lipid, phosphatidylinositol(3,4,5)trisphosphate (PtdIns(3,4,5)P 3). PtdIns(3,4,5)P 3 regulates major aspects of cellular behavior, and the use of both genetic and pharmacological intervention has revealed importan...
Main Authors: | , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2011
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