Defects in NADPH oxidase genes NOX1 and DUOX2 in very early onset inflammatory bowel disease
BACKGROUND and AIMS: Defects in intestinal innate defense systems predispose patients to inflammatory bowel disease (IBD). Reactive oxygen species (ROS) generated by nicotinamide-adenine dinucleotide phosphate (NADPH) oxidases in the mucosal barrier maintain gut homeostasis and defend against pathog...
প্রধান লেখক: | , , , , , , , , , , , , , , , , , , , , , , |
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বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
Elsevier
2015
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