Defects in NADPH oxidase genes NOX1 and DUOX2 in very early onset inflammatory bowel disease

BACKGROUND and AIMS: Defects in intestinal innate defense systems predispose patients to inflammatory bowel disease (IBD). Reactive oxygen species (ROS) generated by nicotinamide-adenine dinucleotide phosphate (NADPH) oxidases in the mucosal barrier maintain gut homeostasis and defend against pathog...

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গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Hayes, P, Dhillon, S, O'Neill, K, Thoeni, C, Hui, K, Elkadri, A, Guo, C, Kovacic, L, Aviello, G, Alvarez, L, Griffiths, A, Snapper, S, Brant, SR, Doroshow, J, Silverberg, MS, Peter, I, McGovern, D, Cho, J, Brumell, J, Uhlig, H, Bourke, B, Muise, A, Knaus, U
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: Elsevier 2015