Modelling multiscale aspects of colorectal cancer

Colorectal cancer (CRC) is responsible for nearly half a million deaths annually world-wide [11]. We present a series of mathematical models describing the dynamics of the intestinal epithelium and the kinetics of the molecular pathway most commonly mutated in CRC, the Wnt signalling network. We als...

詳細記述

書誌詳細
主要な著者: van Leeuwen, I, Byrne, H, Johnston, M, Edwards, C, Chapman, S, Bodmer, W, Maini, P
フォーマット: Journal article
出版事項: 2008