In vitro activity of pyronaridine against multidrug-resistant Plasmodium falciparum and Plasmodium vivax.

Pyronaridine, a Mannich base antimalarial, has demonstrated high in vivo and in vitro efficacy against chloroquine-resistant Plasmodium falciparum. Although this drug has the potential to become a prominent artemisinin combination therapy, little is known about its efficacy against drug-resistant Pl...

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Bibliographic Details
Main Authors: Price, R, Marfurt, J, Chalfein, F, Kenangalem, E, Piera, K, Tjitra, E, Anstey, N, Russell, B
Format: Journal article
Language:English
Published: 2010