Impact on T-cell depletion and CD34+ cell recovery using humanised CD52 monoclonal antibody (CAMPATH-1H) in BM and PSBC collections; comparison with CAMPATH-1M and CAMPATH-1G.

BACKGROUND: Ex vivo T-cell depletion of allogeneic BM (BM) grafts can effectively reduce graft versus host disease (GvHD) and may also apply to transplantation of allogeneic peripheral blood stem cell (PBSC) transplants. METHODS: Here we have evaluated T-cell depletion and progenitor cell recovery...

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Bibliographic Details
Main Authors: Williams, R, Clarke, E, Blair, A, Evely, R, Hale, G, Waldmann, H, Brookes, S, Pamphilon, D
Format: Journal article
Language:English
Published: 2000