CpG oligodeoxynucleotides block human immunodeficiency virus type 1 replication in human lymphoid tissue infected ex vivo.

Oligodeoxynucleotides (ODNs) with immunomodulatory motifs control a number of microbial infections in animal models, presumably by acting through toll-like receptor 9 (TLR9) to induce a number of cytokines (e.g., alpha interferon and tumor necrosis factor alpha). The immunomodulatory motif consists...

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Bibliographic Details
Main Authors: Schlaepfer, E, Audigé, A, von Beust, B, Manolova, V, Weber, M, Joller, H, Bachmann, M, Kundig, T, Speck, R
Format: Journal article
Language:English
Published: 2004