Myeloma cells can promote osteoclastic activity rather than osteoclast recruitment in vitro; Evidence from the 5T2MM murine model of myeloma

Myeloma cells can promote osteoclastic activity rather than osteoclast recruitment in vitro; Evidence from the 5T2MM murine model of myeloma

Manylion Llyfryddiaeth
Prif Awduron:	Mueller, G, Vanderkerken, K, Russell, R, Croucher, P
Fformat:	Conference item
Cyhoeddwyd:	2004

Eitemau Tebyg

5T2MM murine myeloma cells and CD138+ve human myeloma cells promote osteoclastic activity rather than osteoclast formation in vitro
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Cyhoeddwyd: (2004)

The Role of Myeloma Cells to Osteoclast Activation
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Glycosphingolipid synthesis inhibition limits osteoclast activation and myeloma bone disease
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The potent bisphosphonate ibandronate does not induce myeloma cell apoptosis in a murine model of established multiple myeloma.
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An In Vitro Model of Murine Osteoclast-Mediated Bone Resorption
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Apomine, an inhibitor of HMG-CoA-reductase, promotes apoptosis of myeloma cells in vitro and is associated with a modulation of myeloma in vivo.
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Cyhoeddwyd: (2007)

Translational potential of a novel osteoclast inhibitor, eliglustat, in myeloma bone disease
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APOMINE (TM), a novel inhibitor of the meyalonate/isoprenoid pathway, promotes apoptosis of myeloma cells in vitro and is associated with a modulation of the myeloma disease in vivo.
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Cyhoeddwyd: (2002)

Interleukin-32 promotes osteoclast differentiation but not osteoclast activation
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Interleukin-32 promotes osteoclast differentiation but not osteoclast activation.
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Osteoprotegerin and the development of myeloma bone disease
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Zoledronic Acid Inhibits the Capacity of Myeloid-Immune Suppressor Cells in Myeloma to Form Osteoclasts.
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CST6 suppresses osteolytic bone disease in multiple myeloma by blocking osteoclast differentiation
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Osteoclast Immunosuppressive Effects in Multiple Myeloma: Role of Programmed Cell Death Ligand 1
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Bortezomib modulates CHIT1 and YKL40 in monocyte-derived osteoclast and in myeloma cells
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Bisphosphonates and in vivo models of multiple myeloma - Reply
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Osteoprotegerin (OPG) inhibits the development of osteolytic bone disease in the 5T2MM model of multiple myeloma.
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Bisphosphonates--mechanisms of action in multiple myeloma.
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Bisphosphonates and osteoprotegerin as inhibitors of myeloma bone disease.
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The checkpoint inhibitor PD-1H/VISTA controls osteoclast-mediated multiple myeloma bone disease
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BISPHOSPHONATES AFFECT HUMAN OSTEOCLAST DEVELOPMENT IN VITRO
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Recombinant osteoprotegerin decreases tumor burden and increases survival in a murine model of multiple myeloma.
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Osteoclasts in myeloma are derived from Gr-1+CD11b+mononuclear cells of the bone marrow niche
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Osteoclasts in multiple myeloma are derived from Gr-1+CD11b+myeloid-derived suppressor cells
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Glucose Ceramide Synthase Inhibitors Inhibit Osteoclast Activation Induced by Myeloma-Derived and De Novo Synthesized Glycosphingolipids
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Multi-Scale Agent-Based Multiple Myeloma Cancer Modeling and the Related Study of the Balance between Osteoclasts and Osteoblasts.
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A novel phthalimide derivative, TC11, has preclinical effects on high-risk myeloma cells and osteoclasts.
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In vitro generation of mature human osteoclasts.
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Isolation of human osteoclasts formed in vitro: hormonal effects on the bone-resorbing activity of human osteoclasts.
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The Effects of Forodesine in Murine and Human Multiple Myeloma Cells
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Effect of amorphous silica nanoparticles on <it>in vitro </it>RANKL-induced osteoclast differentiation in murine macrophages
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Osteoclasts and Microgravity
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Estrogen receptor gene expression in osteoclasts loss with osteoclast maturation.
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Osteoclast Activation and Inflammatory Bone Diseases: Focusing on Receptors in Osteoclasts
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NK cells support osteoclast formation in vitro
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Activated T lymphocytes support osteoclast formation in vitro.
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NK cells support osteoclast formation in vitro
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The effects of seeding density and osteoclastic supplement concentration on osteoclastic differentiation and resorption
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Ewing's sarcoma cells promote osteoclast formation
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