Minimal residual disease is a significant predictor of treatment failure in non T-lineage adult acute lymphoblastic leukaemia: final results of the international trial UKALL XII/ECOG2993.

The predictive value of molecular minimal residual disease (MRD) monitoring using polymerase chain reaction amplification of clone-specific immunoglobulin or T-cell Receptor rearrangements was analysed in 161 patients with non T-lineage Philadelphia-negative acute lymphoblastic leukaemia (ALL) parti...

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Bibliographic Details
Main Authors: Patel, B, Rai, L, Buck, G, Richards, S, Mortuza, Y, Mitchell, W, Gerrard, G, Moorman, A, Duke, V, Hoffbrand, A, Fielding, A, Goldstone, A, Foroni, L
Format: Journal article
Language:English
Published: 2010