Population pharmacokinetics of the antimalarial amodiaquine: A pooled analysis to optimize dosing

Amodiaquine plus artesunate is the recommended antimalarial treatment in many malaria-endemic countries. However, pediatric doses are largely based on a linear extrapolation from adult doses. We pooled data from previously published studies on the pharmacokinetics of amodiaquine, to optimize the dos...

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Main Authors: Ali, A, Penny, M, Smith, T, Workman, L, Sasi, P, Adjei, G, Aweeka, F, Kiechel, J, Jullien, V, Rijken, M, McGready, R, Mwesigwa, J, Kristensen, K, Stepniewska, K, Tarning, J, Barnes, K, Denti, P, Wwarn Amodiaquine Pk Study Group
格式: Journal article
语言:English
出版: American Society for Microbiology 2018