Two bistable switches govern M phase entry
The abrupt and irreversible transition from interphase to M phase is essential to separate DNA replication from chromosome segregation. This transition requires the switch-like phosphorylation of hundreds of proteins by the cyclin-dependent kinase 1 (Cdk1):cyclin B (CycB) complex. Previous studies h...
| Glavni autori: | , , , , |
|---|---|
| Format: | Journal article |
| Jezik: | English |
| Izdano: |
Cell Press
2016
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